This book introduces time-stretch quantitative phase imaging (TS-QPI), a high-throughput label-free imaging flow cytometer developed for big data acquisition and analysis in phenotypic screening. TS-QPI is able to capture quantitative optical phase and intensity images simultaneously, enabling high-content cell analysis, cancer diagnostics, personalized genomics, and drug development. The authors also demonstrate a complete machine learning pipeline that performs optical phase measurement, image processing, feature extraction, and classification, enabling high-throughput quantitative imaging that achieves record high accuracy in label -free cellular phenotypic screening and opens up a new path to data-driven diagnosis.
Artificial Intelligence in Label-free Microscopy Ebook
Biological Cell Classification by Time Stretch
By: Ata Mahjoubfar; Claire Lifan Chen; Bahram Jalali
Publisher:
Springer
Print ISBN: 9783319514475, 3319514474
eText ISBN: 9783319514482, 3319514482
Copyright year: 2017
Format: PDF
Available from $ 139.00 USD
SKU: 9783319514482
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